However, cancer is an intricate disease and the same genetic mutations can result in varying subtypes of tumors in different individuals. The tool is mostly used to inhibit gene function. This is the first time CRISPR has been used to generate different cancer-causing gain-of-function mutations in mice. Next, to confirm that these isoforms actually caused the variances, they produced them in the mouse without using CRISPR. They found that they were indeed able to generate the two different tumor subtypes with their respective characteristics.

Mutations in the same genes can lead to different subtypes of tumors in different people. Now, Cold Spring Harbor Laboratory Assistant Professor Semir Beyaz has created a new method to model certain liver cancer tumor subtypes using the gene-editing tool CRISPR-Cas9. The tool is mostly used to inhibit gene function. This is the first time CRISPR has been used to generate different cancer-causing gain-of-function mutations in mice. The mutations Beyaz targeted can lead to colon and liver cancers.

The original version of the bill would have made it a crime to slaughter horses and burros for human consumption, but it was amended to instead establish tighter regulations when transporting 20 or more horses for slaughter. The measure has drawn dozens of horse rescuers and mustang advocates to the state Capitol to plead for protection of horses. The United States, including Colorado, is sending an estimated 20,000 horses per year to slaughterhouses in Canada and Mexico, according to recent reports from animal welfare groups and the American Journal of Veterinary Research.

The majority of microplastics resembled the containers in composition, indicating that they “were released from their inner surface.” However, 58% of the particles were made of other polymer types demonstrating that food packaging is not the only source of microplastic contamination in foods. “Microplastics in polystyrene-made food containers from China: abundance, shape, size, and human intake.” Environmental Science and Pollution Research.

Advanced fibrosis, as measured by liver stiffness scores, is associated with a greater likelihood of liver cancer among people with chronic hepatitis C or fatty liver disease, according to findings published in PLOS One. During the study period, 496 people in the hepatitis C group and 42 people in the NAFLD group developed HCC. Among people with hepatitis C, the incidence of hepatocellular carcinoma rose with liver stiffness scores; however, 119 people without advanced cirrhosis nonetheless developed liver cancer.

March 9th, 2023 Proteins are made up of amino acids. It is known that reducing only protein in the diet, while maintaining the same calorie intake, produces a modest slowing of aging. In today's open access paper, researchers compare overall protein restriction with restriction of only the essential amino acid isoleucine, in both cases maintaining an overall calorie intake equivalent to that of a non-restricted diet.

The review highlights the current technologies for commercially developing and growing microalgae, as well as the scientific and economic challenges to scaling production. While long studied as a source of biofuel thanks to their high lipid or fat content, algae are also attracting interest from researchers because of their potential to be a more efficient food source. In the paper, the UCSD authors describe the various scientific tools available to produce the most desirable traits for a commercially viable algal product.

Researchers are now looking for different ways of growing nutritious foods to replace the ones whose cultivation is no longer as sustainable. One of these is algae.