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Pars plana vitrectomy improves retinal reattachment but not visual acuity: JAMA
A recent article published in JAMA Ophthalmology found that pars plana vitrectomy improves anatomic outcomes of diabetic tractional retinal detachment but not the functional outcome. The main outcomes of the study included the rate of failure of retinal reattachment after one surgery and final visual acuity. The results of this systematic review and meta-analysis suggest that PPV is an effective strategy to achieve retinal reattachment in individuals with dTRD.
SourceMedical Dialogues
Feb 17, 2023 1
Study compares pharmacologic treatments for managing tooth extraction pain
A recent study published in the Journal of Dental Research has compared the effectiveness of ten pharmacological interventions in order to develop guidelines for acute pain management after tooth extraction in adults. The National Academies’ report entitled “Framing Opioid Prescribing Guidelines for Acute Pain”, highlighted the need to formalize evidence-based alternatives to opioid analgesics in a clinical practice guideline.
SourceMedical Xpress + 6 others
Jan 30, 2023 7
Pneumonia Risk in Patients on DMARD, Glucocorticoid Therapy for Rheumatoid Arthritis
DMARDs are the most commonly used treatment for patients with rheumatoid arthritis but have been linked with pulmonary infections like pneumonia. This population is particularly vulnerable to negative outcomes when infected with pneumonia, and glucocorticoids are often used concurrently. However, according to investigators, there's little known about the relationship between glucocorticoids and pneumonia in patients with rheumatoid arthritis.
SourceHCPLive + 1 other
Jan 26, 2023 2
Study: NSAIDs beat opioids for pain management
According to the findings, interventions classified as the most effective for pain relief were ibuprofen 200 to 400 mg plus acetaminophen 500 to 1,000 mg, acetaminophen 650 mg plus oxycodone 10 mg, ibuprofen 400 mg, and naproxen 400 to 440 mg. Further, NSAIDs with or without acetaminophen resulted in better pain-related outcomes than opioids with or without acetaminophen or placebo, the researchers found.
Jan 19, 2023 1
Pars Plana Vitrectomy Associated with High Retinal Reattachment, but Low Final Vision
Pars plana vitrectomy may be an effective strategy to achieve retinal reattachment after tractional retinal detachment in people with diabetes, although final postoperative visual acuity remained low in these patients. Meanwhile, the meta-analysis of overall final VA included 20 studies. Regarding functional outcomes, the data show only baseline VA was significantly associated with final VA in a multivariable model.
SourceHCPLive + 1 other
Jan 12, 2023 2
New year, new genes
Van der Sanden et al. provide evidence that genome sequencing is a valuable first tier test; one reason being that it can identify copy number variants likely to be missed by exome sequencing. Boehm et al. utilise genome sequencing to identify a missense variant in PAX6 associated with diabetes. Koopmann et al. utilised exome sequencing to identify LDB3 variants as a novel cause of cardiomyopathy.
SourceNature Genetics
Jan 06, 2023 1
High-flow oxygen therapy not superior to NIV/ LFOT as rescue therapy in kids
In randomized controlled trials, non-RCTs, and cohort studies where high-flow nasal cannula was compared with traditional low-flow oxygen treatment and/or noninvasive ventilation, patients under 24 months old with bronchiolitis who need noninvasive respiratory support were included. When it comes to lowering oxygen days and treatment failure, HFNC outperforms LFOT. High-flow oxygen and other noninvasive respiratory support therapies in bronchiolitis: Systematic review and network meta-analyses.
SourceMedical Dialogues
Dec 25, 2022 1
Trend of anaesthesia research from SAARC countries. A decade’s bibliographic analysis of indexed journals of Pakistan
The current study was planned to fill the gap by quantifying and analysing the type of research in the field of anaesthesiology contributed by authors from SAARC countries and published in indexed journals of Pakistan. The current bibliographical analysis showed the contribution of South Asian countries to research in anaesthesiology and its subspecialties published in the five indexed journals of Pakistan, and the results showed that very little research from SAARC countries was being published in Pakistan. Other SAARC countries do not have indexed anaesthesia journals.
Sep 28, 2022 1
Some Funders Are Embracing 'Trust-Based Philanthropy’ by Giving Money Without Lots of Obligations
With most foundations, the board of directors, and top executives set all funding priorities. Nonprofits seeking money from those funders, in turn, must demonstrate an intention to do work that conforms to those priorities. Any nonprofit awarded a grant must follow the funder’s priorities and comply with all of its reporting requirements — which, with some foundations, can be very time-consuming. We are unable to fully display the content of this page.
SourceChronicle of Philanthropy
May 10, 2022 13
NEW: Giving people money with no strings attached is good for their health, dozens of studies indicate  
In addition, there is some evidence that people who got cash payments spent more money on health care. Many of these cash-transfer pilots and experiments – often called basic income programs – have required people to do something to receive the money, such as making sure their children regularly attend school. Other programs, like those we studied, have no such requirements. Our team plans to study whether cash-payment programs that require compliance with conditions lead to better health too. + 3 others
May 10, 2022 5