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JMJD6 protects against isoproterenol-induced cardiac hypertrophy via inhibition of NF-κB activation by demethylating R149 of the p65 subunit
Cardiac-specific JMJD6 overexpression in rats protected the hearts against ISO-induced cardiac hypertrophy and fibrosis, and rescued cardiac function. Histone H4R3 symmetric di-methylation by prmt5 protects against cardiac hypertrophy via regulation of Filip1L/beta-catenin. Prevention of cardiac hypertrophy and heart failure by silencing of NF-kappaB. Yu S, Li Y, Zhao H, Wang Q, Chen P. The Histone demethylase JMJD1C regulates CAMKK2-AMPK signaling to participate in cardiac hypertrophy.
SourceActa Pharmacologica Sinica
Apr 25, 2023 1
Autonomous Self-Burying Seed Carriers for Aerial Seeding #Biomimicry
SourceZephyrnet.com
Mar 22, 2023 1
Engineered magic: Wooden seed carriers mimic the behavior of self-burying seed
How seeds implant themselves in soil can seem magical. When it begins to unwind, the twisting tail engages with the ground, causing the seed carrier to push itself upright. Further unwinding creates torque to drill down into the ground, burying the seed. But erodium’s one-tailed carrier only works well on soils with crevices. To employ their E-seed carriers in a broader range of environments, the research team developed a three-tailed version that is more efficient at pushing itself upright.
SourceUniversity of Pennsylvania
Mar 03, 2023 1
SciTech Roundup 2/27
In addition, for each hour of sleep lost, students experience a 0.07 decrease in end-of-term GPA, suggesting that the effects of even one night of lost sleep at the beginning of a semester can hurt a student at the end of the semester. In these cases, a seed carrier called E-seed developed by researchers from the Morphing Matter Lab, directed by Lining Yao and published in "Nature," can help bury these seeds deeper into the ground. One way of reducing air pollution is to increase the efficiency of the grid system.
SourceCarnegie Mellon Tartan
Feb 27, 2023 1
A New Twist On Sowing Seeds
So we designed this three-tailed self-burying seed carrier. This is inspired by how the natural seeds, a natural grass species called Erodium seeds can self bury into the ground. Like, what is the use of these seeds? So we looked into the apparent practice of aerial delivery of seeds.
SourceScience Friday
Feb 24, 2023 1
Go bury yourself: Engineers design wooden seed carriers that drill down in the soil when exposed to rainfall
The technology could be used to improve the efficiency of aerial seeding. Some seeds can implant themselves in soil like tiny drills and the mechanism of one such genus of plant has inspired a new engineered seed carrier that can successfully bury itself down in the soil 80% of the time. As the stalk begins to unwind, its twisting tail connects with the ground and causes the seed carrier to push itself upright. According to co-author Andreea Danielescu, director of the Future Technologies R&D group at Accenture Labs in the US, E-seed could be used to improve ecological resilience.
SourceCosmos Magazine
Feb 17, 2023 1
Plant-inspired E-seeds drill themselves into the dirt when moistened
SourceNew Atlas
Feb 15, 2023 1
This bioinspired seed carrier has an 80 percent success rate
The researchers designed a wood-based biodegradable seed system comprising a seed carrier with three coiled tails. A drone will disperse the seed carriers. The researchers compared natural Erodium seed's success under the same terrain conditions and found the success rate to be zero percent. Our three-tailed carrier has an 80% drilling success rate on fat land after two triggering cycles, due to the beneficial resting angle of its tail anchoring, whereas the natural Erodium seed’s success rate is 0%.
SourceInteresting Engineering
Feb 15, 2023 1
Engineered magic: Wooden seed carriers mimic the behavior of self-burying seeds
How seeds implant themselves in soil can seem magical. Danli Luo, a former research assistant at the Morphing Matter Lab and the lead author of the Nature paper, said design and construction of the seed carrier were inspired by the self-burying mechanism that Erodium evolved as it adapted to arid climates. Further unwinding creates torque to drill down into the ground, burying the seed. But Erodium's one-tailed carrier only works well on soils with crevices. "Seeds have a magic response to rain," Yao said.
SourcePhysOrg.com + 3 others
Feb 15, 2023 4
Neighborhood walkability linked to risk of gestational diabetes
A new study by scientists in the Columbia University Mailman School of Public Health’s Built Environment and Health Research Group finds that higher neighborhood walkability is associated with lower risk of gestational diabetes. The researchers, working in partnership with the New York City Department of Health and Mental Hygiene, analyzed the relationships between neighborhood walkability for pregnant New Yorkers.
SourceMedical Xpress + 6 others
Feb 03, 2023 7